Not known Facts About Conolidine alkaloid for chronic pain
Most not long ago, it has been determined that conolidine and the above derivatives act around the atypical chemokine receptor 3 (ACKR3. Expressed in identical areas as classical opioid receptors, it binds to a wide array of endogenous opioids. Contrary to most opioid receptors, this receptor acts for a scavenger and does not activate a 2nd messeng